Plucky, pint-sized hero Stuart Little (Michael J. Fox) returns along with his parents Mr. and Mrs. Little, (Hugh Laurie and Geena Davis), his brother George (Jonathan Lipnicki), and their cat Snowbell (Nathan Lane). Stuart must journey through the city with a reluctant Snowbell to rescue his new friend, free-spirited bird Margalo (Melanie Griffith), from a villainous Falcon (James Woods), proving once again that despite his size, great things can truly come in small packages.